Acquired Thrombophilic Hypercoagulable States Seen in Patients with Liver Cirrhosis: A Single Center Study

Among the common hemostatic issues of patients liver cirrhosis, deep venous thrombosis, pulmonary embolism, and intrahepatic thrombus development are more often ignored. With an estimated frequency ranging from 0.6 to 26 percent, portal thrombosis is another potentially dangerous consequence cirrhosis. Objectives: To determine various acquired thrombophilic / hypercoagulable states seen in with Study design: Descriptive, cross sectional. Settings: Department Medicine, Allied Hospital, Faisalabad duration: 30th June 2019 29th December Materials & Methods: Cirrhosis cases age 25 75 years old both genders were included study. Patients HCC, heritable thrombophilias such as Factor V leiden mutation, congenital budd chiari, cholestatic disorders primary biliary cirrhosis (PBC) sclerosing cholangitis also eliminated. assess for hepatic decompensation, ultrasonography, LFTs, other baseline procedures performed. Doppler USG was performed each case assistance Radiology Hospital DVT, Budd-Chiari syndrome, Portal thrombosis. Results: Mean enrolled 52.08 ± 10.47 years. these 840 patients, 461 (54.88%) male 379 (45.12%) females (ratio 1.2 : 1). AST levels 77.49 8.93 units/liter. ALT 88.51 9.17 total bilirubin 8.33 1.65 mg/dl. Frequency follows; vein 136 (16.19%) chiari syndrome 102 (12.14%), 96 (11.43%) embolism 108 (12.86%) patients. Conclusion: This study concluded that quite high. Keywords: states,